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ANAL ATRESIA OR IMPERFORATE ANUS BIRTH DEFECT Anal Atresia  / Imperforate Anus Birth Defects Potentially Linked to Antidepressants Taken by Mothers During Pregnancy The Mulligan Law Firm and www.drugrxrecall.com is actively evaluating potential Anal Atresia cases originating from any of the 50 states. If you or somebody you know took an antidepressant, such as Zoloft®, while pregnant and your child was born with an Anal Atresia or other birth defect, you should contact our lawyers immediately.
You may be entitled to compensation. We are actively seeking birth defects claims like these in order to represent the legal interests of children and families affected by the manufacturer's potential failure to warn mothers of the potential for congenital birth defects as a result of taking their products. What is an Anal Atresia? An Anal Atresia is a congenital birth defect in which the infant's anal area is malformed.  There are several forms of imperforate anus: a)      A low lesion, in which the colon remains close to the skin. In this case, there may be narrowing of the anus, or the anus may be missing altogether, with the rectum ending in a pouch. b)      A high lesion, in which the colon is higher up in the pelvis and there is a fistula connecting the rectum and the bladder, urethra or the vagina. c)       A persistent cloaca , in which the rectum, vagina and urinary tract are joined into a single channel. Imperforate anus is usually present along with other birth defects—spinal problems, heart problems, tracheoesophageal fistula, esophageal atresia, renal anomalies, and limb anomalies are among some of the possibilities. The extent and seriousness  of anal atresias will vary with each individual case. What SSRI Antidepressants Are Potentially Linked to Anal Atresia? The following antidepressants are the primary drugs potentially linked to the development of Anal Atresia in newborn infants and babies if their mothers took these drugs during pregnancy: - Symbyax® (fluoxetine and olanzapine)
- Generics and other types of this class of drugs (SSRI).
Anal Atresia Repair Imperforate anus birth defects usually require immediate surgery to open a passage for feces unless a fistula can be relied on until corrective surgery takes place.
Depending on the severity of the imperforate, it is treated either with a perineal anoplasty or with a colostomy. The goal of surgery is to repair the defect to the best possible outcome; sometimes more than one surgery is necessary. Do I Have an Anal Atresia Lawsuit? Our attorneys are currently accepting potential Anal Atresia and related birth defect claims originating in any of the 50 states. Please contact us for a free questionnaire and additional information that we will promptly mail you. If you or somebody you know took an antidepressant during pregnancy and your child was born with an Anal Atresia, you should contact us immediately. You may be entitled to compensation.  Do not delay, as failure to act may cause your legal rights to be lost if your statute of limitations passes. Your birth defect claim may be helpful to others as it may help protect other babies from the same birth defect by helping to send a clear message to the large pharmaceutical companies that their potential failure to properly warn and other potential behavior is unacceptable. Therefore, your legal action can possibly help this unfortunate side effect become better known, and also possibly encourage companies to provide better warnings that this type of side effect can occur. Who We Are The Mulligan Law Firm, a national law firm located in Dallas, Texas, provides legal information and resources for injured individuals and their families. The firm has successfully resolved over $600,000,000 in claims for its clients. Formed in 1995, it has been helping people for over 15 years, with the strength and experience to represent plaintiffs in all 50 states. We take all cases on a contingency-fee basis, which means you do not pay for our services unless you receive an award or compensation. Do not delay, as your rights and compensation may be lost forever if you wait. Statutes of limitations vary by state, and failure to act immediately may cause you to lose your potential legal rights forever. Paxil® is a registered trademark of SmithKline Beecham Corporation, Prozac ®is a registered trademark of Eli Lilly and Company. Zoloft® is a registered trademark of Pfizer Inc., Lexapro® is a registered trademark of Forest Laboratories, Inc., Celexa® is a registered trademark of Forest Laboratories, Inc., Effexor is a registered trademark of Wyeth Corporation, Symbyax® is a registered trademark of Eli Lilly and Company. Wellbutrin® is a registered trademark of GlaxoSmithKline LLC. Please see terms and conditions for use of this site at www.drugrxrecall.com. We thank Wikipedia for the information below and encourage you to support their work. Please see main article, Discussion Tab, Contributors List, and additional information on this article here: http://en.wikipedia.org/wiki/Anal_Atresia Imperforate anus From Wikipedia, the free encyclopedia (Redirected from Anal Atresia) Imperforate anus Classification and external resources An X-ray showing Imperforate anus
MedlinePlus eMedicine An imperforate anus or anal atresia is a birth defect in which the rectum is malformed. Its cause is unknown. Features  There are several forms of imperforate anus:  A low lesion, in which the colon remains close to the skin. In this case, there may be a stenosis (narrowing) of the anus, or the anus may be missing altogether, with the rectum ending in a blind pouch.  A high lesion, in which the colon is higher up in the pelvis and there is a fistula connecting the rectum and the bladder, urethra or the vagina.  A persistent cloaca (from the term cloaca, an analogous orifice in reptiles and amphibians), in which the rectum, vagina and urinary tract are joined into a single channel.
Imperforate anus is usually present along with other birth defects—spinal problems, heart problems, tracheoesophageal fistula, esophageal atresia, renal anomalies, and limb anomalies are among the possibilities.[1]
 Associated anomalies
Imperforate anus is associated with an increased incidence of some other specific anomalies as well, together being called the VACTERL association:  V - Vertebral anomalies  A - Anal atresia  C - Cardiovascular anomalies  T - Tracheoesophageal fistula  E - Esophageal atresia  R - Renal (Kidney) and/or radial anomalies  L - Limb defects  Diagnosis When an infant is born with an anorectal malformation, it is usually detected quickly as it is a very obvious defect. Doctors will then determine the type of birth defect the child was born with and whether or not there are any associated malformations. It is important to determine the presence of any associated defects during the newborn period in order to treat them early and avoid further sequelae. There are two main categories of anorectal malformations: those that require a protective colostomy and those that do not. The decision to open a colostomy is usually taken within the first 24 hours of birth. Sonography can be used to determine the type of imperforate anus.[2] Treatment Imperforate anus usually requires immediate surgery to open a passage for feces unless a fistula can be relied on until corrective surgery takes place. Depending on the severity of the imperforate, it is treated either with a perineal anoplasty[3] or with a colostomy. Prognosis With a high lesion, many children have problems controlling bowel function and most also become constipated. With a low lesion, children generally have good bowel control, but they may still become constipated.
For children who have a poor outcome for continence and constipation from the initial surgery, further surgery to better establish the angle between the anus and the rectum may improve continence and, for those with a large rectum, surgery to remove that dilated segment may significantly improve the bowel control for the patient. An antegrade enema mechanism can be established by joining the appendix to the skin (Malone stoma); however, establishing more normal anatomy is the priority. Epidemiology Imperforate anus has an estimated incidence of 1 in 5000 births.[4][5] It affects boys and girls with similar frequency.[6] However, imperforate anus will present as the low version 90% of the time in females and 50% of the time in males. Imperforate anus is an occasional complication of sacrococcygeal teratoma.[7]
References
 1.^ Colorectal Center, Cincinnati Children's Hospital Medical Center. "Anorectal Malformations / Imperforate Anus." Retrieved July, 2005.  2.^ Haber HP, Seitz G, Warmann SW, Fuchs J (2007). "Transperineal sonography for determination of the type of imperforate anus". AJR. American journal of roentgenology 189 (6): 1525–9. doi:10.2214/AJR.07.2468. PMID 18029895.  3.^ Becmeur F, Hofmann-Zango I, Jouin H, Moog R, Kauffmann I, Sauvage P (2001). "Three-flap anoplasty for imperforate anus: results for primary procedure or for redoes". European Journal of Pediatric Surgery 11 (5): 311–4. doi:10.1055/s-2001-18555. PMID 11719868.  4.^ Texas Pediatric Associates. "Imperforate anus." Retrieved 13 July 2005.  5.^ MedLine Plus. "Imperforate anus." Retrieved 13 July 2005.  6.^ Adotey JM, Jebbin NJ (2004). "Anorectal disorders requiring surgical treatment in the University of Port Harcourt Teaching Hospital, Port Harcourt". Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria 13 (4): 350–4. PMID 15523860.  7.^ Bhat NA, Mathur M, Bhatnagar V (2003). "Sacrococcygeal teratoma with anorectal malformation". Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 22 (1): 27. PMID 12617452. External links Medline Plus Medical Encyclopedia: Imperforate anus v · d · eCongenital malformations and deformations of digestive system (Q35–Q45, 749–751) Upper GI tract
Tongue, mouth and pharynx Cleft lip and palate ·Van der Woude syndrome ·tongue (Ankyloglossia, Macroglossia, Hypoglossia) Esophagus
EA/TEF (Esophageal atresia: types A, B, C, and D, Tracheoesophageal fistula: types B, C, D and E)  esophageal rings (Esophageal web · upper, Schatzki ring · lower)  Stomach
Pyloric stenosis ·Hiatus hernia Lower GI tract  Intestines  Intestinal atresia (Duodenal atresia) ·Meckel's diverticulum ·Hirschsprung's disease ·Intestinal malrotation ·Dolichocolon ·Enteric duplication cyst  Rectum/anal canal
Imperforate anus ·Persistent cloaca
Accessory
Pancreas Annular pancreas ·Accessory pancreas ·Johanson–Blizzard syndrome
Pancreas divisum
Bile duct
Choledochal cysts (Caroli disease) ·Biliary atresia
Liver
Alagille syndrome ·Polycystic liver disease
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